Adapted from Margaret Atwood's bestselling novel, "The Handmaid's Tale" is set in the dystopian Gilead, a totalitarian society in what was formerly part of the United States. Facing environmental disasters and a plunging birthrate, Gilead is ruled by a twisted religious fundamentalism that treats women as property of the state.

As one of the few remaining fertile women, Offred (Elisabeth Moss) is a Handmaid in the Commander's household, one of the caste of women forced into sexual servitude as a last desperate attempt to re-populate a devastated world. In this terrifying society where one wrong word could end her life, Offred navigates between Commanders, their cruel Wives, domestic Marthas, and her fellow Handmaids - where anyone could be a spy for Gilead - all with one goal: to survive and find the daughter that was taken from her.