Jessica and Lennon, best friends forever, live on opposite sides of the country with the different men in their lives. But when Jessica is served divorce papers, she reluctantly moves back to New York and back into Lennon's apartment. It doesn't take long for the girls to fall back into old habits: beloved traditions, Steel Magnolias marathons, epic girl-talk sessions... none of which is good news to Lennon's live-in boyfriend, Joe. He's trying to be understanding, but begins to feel like a stranger in his own home. It doesn't help that his new houseguest accidentally keeps seeing him naked.

Meanwhile, Jessica is just trying to get used to the single life again. She's doing everything from buying new underwear to reconnecting with old friends, like Rav, who may or may not have feelings for her. She hasn't spoken to him since he punched her ex-husband in the face at their wedding... but somehow, that doesn't seem like such a big deal anymore. Girls will be girls and men will forever be on the outside looking in!