"Do Not Disturb" is a workplace comedy set at one of New York City's hottest and hippest hotels: The Inn. Named one of the Big Apple's "10 Best Places to Stay," The Inn is just that - the "in" place to be, with its chic decor, stylish staff and celebrity clientele. Behind the scenes, however, the upstairs/downstairs dynamic tells quite a different story.

The hotel's top-notch reputation and sophisticated look is due in large part to Neal (Jerry O'Connell) - at least in his opinion. Neal is the egotistical, womanizing general manager who will do whatever it takes to make sure the hotel is considered the best party in town.

Rhonda (Niecy Nash) is the head of Human Resources who also keeps Neal's demands in check. She's brash, fabulous and brutally honest and runs the HR department from her bullpen downstairs with a set of rules that are all her own. Rhonda does her best to keep the back of the house in line and the front of the house out of trouble.

At the front desk handling check-in while wearing 6-inch Manolos is Nicole (Molly Stanton), an aging model who is svelte, cynical and slightly starving.

The downstairs staff includes Molly (Jolene Purdy), a reservations clerk who dreams of pop-singer stardom as much as she craves to be part of the action upstairs; and Larry (Jesse Tyler Ferguson), the head of housekeeping, who spends more time on the phone cleaning up his messes at home than he does cleaning up after the guests upstairs.