AceShowbiz - Christina Applegate has been living with multiple sclerosis (MS) in the past few years. In a series of frank discussions on her podcast, "MeSsy," co-hosted with Jamie-Lynn Sigler, she offers a raw look into the daily struggles and unexpected challenges of this chronic illness.

Since her diagnosis in 2021, she has faced a whirlwind of hospital visits and medical tests. "For three years, since I was diagnosed, I've been in the hospital upwards of 30 times from throwing up and diarrhea and pain," she revealed.

These relentless symptoms led to an exhaustive series of tests, yet answers remained elusive until recently.

"Talk to your doctor about motility issues," she advised listeners. "Because one of the things with MS is that it slows down our organs... there is a slowing of the function of your organs."

Despite her neurologist's reservations about such symptoms being directly linked to MS, Applegate remains convinced there's a connection.

The actress, known for her roles in "Dead to Me" and "Samantha Who?", also shared the severity of her condition's daily impact. "I lay in bed screaming. Like, the sharp pains, the ache, the squeezing," Applegate confessed.

These symptoms sometimes limit her ability to perform simple tasks, like picking up her phone or remote, as the pain extends to her hands.

In parallel, Jamie-Lynn Sigler's journey with MS began when she was only 20 years old. "I lived in a state of denial," Sigler admitted on the podcast, reflecting on her early years post-diagnosis.

She avoided acknowledging her condition publicly, fearing it would affect her career and personal life. "I felt like if I didn't talk about my MS, it wasn't real," she explained, an approach she now realizes exacerbated her suffering.

Through their podcast, Applegate and Sigler have created a platform for open dialogue about MS, breaking the silence surrounding this often-misunderstood disease. They've built a community where personal stories of resilience and hope are shared, offering support to others facing similar battles.

In a heartfelt note, Sigler praised her co-host, "One year of MeSsy. Thank you to Christina, without you none of this would be possible... The human spirit is incredible, and getting to connect with so many people's stories of resiliency and hope has forever changed me."

By shedding light on their personal struggles, Christina Applegate and Jamie-Lynn Sigler are not just bringing awareness to multiple sclerosis; they're fostering a sense of solidarity and inspiring others to confront and share their battles openly.