Greg Pritchard and his small daughter Kyla go missing while on the morning school run. Despite the proclamation from Kyla's mother Sarah that is all is good with her family, the team suspects that something is going on below the surface, especially when they uncover information that suggests Greg is far from the model citizen all who knew him make him out to be. Following witness reports, a web of lies and secrecy is revealed, a web that includes connections to drug dealers and a high-profile murder case. When Jack and his squad dig into Greg's murky past, they discover that the key to solving the case could lie in the FBI building, specifically within the Witness Protection Program.