While Sheriff Lucilia Cable (Jennifer Beals) searches for Alec unsuccessfully, Abby theorizes that it was more than an accident and retrieves his video journals from Daniel Cassidy (special guest star Ian Ziering). When one of her patients, Susie Coyle (guest star Elle Graham), escapes from the hospital, Abby and Matt follow her into the swamp. There, Abby encounters Swamp Thing – a creature that Susie later identifies as Alec Holland.
While Alec struggles to understand his metamorphosis into the monstrous, plant-based creature, known as Swamp Thing, Avery meets with Jason Woodrue (Kevin Durand), the scientist who initially developed the biological accelerant responsible for the "green flu" and orders him to halt the epidemic. And Maria Sunderland (Virginia Madsen) reaches out to Madame Xanadu (Jeryl Prescott) in order to communicates with her dead daughter, Shawna (guest star Given Sharp).
