Clark (Tom Welling) must solve the riddle of the mysterious Nicodemus flower and Lex's (Michael Rosenbaum) shady involvement after it infects the residents of Smallville removing their inhibitions - Jonathan (John Schneider) becomes a couch potato, Lana (Kristin Kreuk) puts the moves on Clark as the town Lolita and Pete (Sam Jones III) tries to kill Lex - then puts them into a deadly coma.