Sung, Hooten and Villanueva join forces to convince Trisha Miller (guest star Cozi Zuehlsdorff), a 13-year-old girl with an advanced brain stem glioma, to try surgery one last time before giving up. Shaken from losing a patient, Ty turns to Dr. Tina Ridgeway (Jennifer Finnigan) for support. Meanwhile, Dr. Buck Tierney (Bill Irwin) tries to bully resident Michelle Robideux (Emily Swallow) into pronouncing a potential organ donor brain dead. And Sydney enlists Villanueva's help diagnosing a patient under the care of internist Dr. John Lieberman (guest star Jonathan Silverman).
