Buckle up for a high-altitude nightmare where the only in-flight entertainment is a fight for survival. Directed by David Ellis, this relentless action-thriller stars Samuel L. Jackson as FBI agent Neville Flynn, tasked with escorting a crucial witness, Sean Jones (Nathan Phillips), from Hawaii to Los Angeles. Their routine flight takes a horrifying turn when an assassin releases a crate of hundreds of the deadliest serpents into the passenger cabin. With the venomous creatures slithering through every compartment, Flynn must take charge of a terrified group of passengers and crew, including a resourceful flight attendant (Julianna Margulies) and a panicked rap star (Kenan Thompson). As the snakes strike with lethal precision and chaos erupts at 30,000 feet, the survivors must use their wits and whatever they can find to battle the reptilian onslaught before the plane—and everyone on it—meets a gruesome end.