A lonely, down-on-her-luck waitress, Molly (Alexis Bledel), meets a handsome, quirky jewelry store clerk, Gus (Zachary Levi), and thinks that maybe - finally -- she's met Mr. Right.

The more Molly gets to know Gus, the more she's intrigued by him. But she's also mystified and sometimes miffed. Gus is absent? minded and preoccupied. Is there already a girlfriend in his life? Is he harboring some big secret? In other words, Molly wonders, what's his problem? Well, Gus' "problem" is that three years ago he suffered a brain aneurysm. He'd been a brilliant young astrophysicist; now he's totally lost his short? term memory. Every day is a brand new day and his life starts anew. And every day when he sees Molly, he's unable to connect the dots and recognize how, exactly, she fits into his life. But there's something about this beautiful, sensitive, funny woman that makes Gus fall in love with her all over again - every day.