Deep in the Amazon rainforest, a daring riverboat captain named Frank Wolff (played by The Rock) navigates treacherous waters and supernatural dangers aboard his rickety vessel, La Quila. When the brilliant and determined British scientist Dr. Lily Houghton (played by Emily Blunt) arrives seeking a mythical tree with legendary healing powers, she enlists Frank's reluctant help for an expedition into uncharted jungle. Together with her refined brother MacGregor (played by Jack Whitehall), the mismatched trio must outrun a menacing German aristocrat (played by Jesse Plemons) and a cursed conquistador (played by Edgar Ramirez) who guards the forest's darkest secrets. Directed by Jaume Collet-Serra, this rollicking adventure blends pulse-pounding action with witty banter and eerie supernatural elements, as Frank and Lily discover that the jungle itself holds ancient forces far more dangerous than any rival treasure hunter. Along the way, their clashing personalities spark an unexpected chemistry that threatens to upend both their quests.