(*): W=Win, N=Nomination
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2017 | N | Best Supporting Actor in a Film | Rogue One: A Star Wars Story (2016) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2011 | W | Original Screenplay | Abel (2011) | Augusto Mendoza |
| 2011 | N | - | Abel (2010) | - |
| 2011 | N | Best Direction (Mejor Direccion) | Abel (2010) | - |
| 2009 | N | Best Actor (Mejor Actor) | Rudo y Cursi (2008) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2009 | W | Best Acting Ensemble | Milk (2008) | Sean Penn, James Franco, Josh Brolin |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2009 | N | Best Actor (Mejor Actor) | Solo quiero caminar (2008) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2019 | N | Best Actor in a Drama Series | Narcos: Mexico (2018) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2009 | N | Best Actor (Mejor Actor) | Solo Quiero Caminar (2008) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2015 | N | Best Actor - Feature Film | The Book of Life (2014) | - |
| 2012 | W | Best Supporting Actor - Feature Film | Casa De Mi Padre (2012) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2002 | W | MTV North Feed (mostly Mexico) - Best Insult (Mejor Insulto) | Y tu mama tambien (2001) | Gael Garcia Bernal |
| 2002 | W | MTV North Feed (mostly Mexico) - Best Kiss (Mejor Beso) | Y tu mama tambien (2001) | Maribel Verdu |
| 2002 | N | MTV North Feed (mostly Mexico) - Best Kiss (Mejor Beso) | Y tu mama tambien (2001) | Gael García Bernal |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2004 | W | Best Diego Luna in a Movie (Mejor Diego en una Pelicula) | Nicotina (2003) | - |
| 2004 | W | Favorite Actor (Actor Favorito) | Nicotina (2003) | - |
| 2004 | W | Worst Smoker (Peor Fumador) | Nicotina (2003) | - |
| 2004 | N | Best Diego Luna in a Movie (Mejor Diego en una Pelicula) | Open Range (2003) | - |
| 2004 | N | Best Diego Luna in a Movie (Mejor Diego en una Pelicula) | Soldados de Salamina (2003) | - |
| 2004 | N | Best Turn-On (Mejor Cachondez); For the cyber voyeurism. | Nicotina (2003) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2017 | N | #Squad | Rogue One: A Star Wars Story (2016) | Felicity Jones, Forest Whitaker, Ben Mendelsohn, Alan Tudyk, Donnie Yen, Riz Ahmed, Mads Mikkelsen |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2014 | N | Can He Act or What? | - | - |
| 2007 | N | !Que actorazo! (Can He Act or What?) | Solo Dios Sabe (2005) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2010 | N | Best Film | Abel (2010) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2009 | N | Outstanding Performance by a Cast in a Motion Picture | Milk (2008) | Sean Penn, James Franco, Josh Brolin |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2017 | N | Choice Sci-Fi Movie Actor | Rogue One: A Star Wars Story (2016) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2001 | W | - | Y tu mama tambien (2001) | Gael Garcia Bernal |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2001 | W | - | Y tu mama tambien (2001) | Gael Garcia Bernal |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2015 | W | Best Original Song Written Directly for a Film | "The Apology Song" from movie "The Book of Life" | Gustavo Santolalla, Paul Williams |
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