(*): W=Win, N=Nomination
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2009 | N | Outstanding Lead Actress in a Miniseries or a Movie | Accidental Friendship (2008) (TV Movie) | - |
| 2009 | N | Outstanding Supporting Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| 2008 | N | Outstanding Supporting Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| 2007 | N | Outstanding Supporting Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| 2006 | N | Outstanding Supporting Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2015 | N | Outstanding Supporting Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| 2014 | N | Outstanding Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| 2013 | N | Outstanding Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| 2012 | N | Outstanding Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| 2011 | N | Outstanding Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| 2010 | W | Outstanding Directing in a Dramatic Series | Grey's Anatomy (2005) (TV) - for ep. 'Give Peace a Chance' | - |
| 2010 | N | Outstanding Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| 2009 | N | Outstanding Actress in a Television Movie, Mini-Series or Dramatic Special | Accidental Friendship (2008) (TV Movie) | - |
| 2008 | W | Outstanding Supporting Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| 2008 | W | Outstanding Supporting Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| 2007 | W | Outstanding Supporting Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| 2006 | N | Outstanding Supporting Actress in a Drama Series | Grey's Anatomy (2005) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2008 | W | Favorite Scene Stealing Star | Grey's Anatomy (2005) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2009 | W | Performance in a TV Movie or Miniseries | Accidental Friendship (2008) (TV Movie) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2008 | N | Best Actress in a Supporting Role in a Series, Mini-Series or Motion Picture Made for Television | Grey's Anatomy (2005) (TV) | - |
| 2007 | N | Best Actress in a Supporting Role in a Series, Mini-Series or Motion Picture Made for Television | Grey's Anatomy (2005) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2008 | N | Outstanding Performance by an Ensemble in a Drama Series | Grey's Anatomy (2005) (TV) | Eric Dane, Patrick Dempsey, Katherine Heigl |
| 2007 | W | Outstanding Performance by an Ensemble in a Drama Series | Grey's Anatomy (2005) (TV) | Eric Dane, Patrick Dempsey, Katherine Heigl |
| 2007 | W | Outstanding Performance by a Female Actor in a Drama Series | Grey's Anatomy (2005) (TV) | Eric Dane, Patrick Dempsey, Katherine Heigl |
| 2006 | N | Outstanding Performance by an Ensemble in a Drama Series | Grey's Anatomy (2005) (TV) | Patrick Dempsey, Katherine Heigl, T.R. Knight |
| 2004 | W | Outstanding Performance by a Female Actor in a Drama Series | Grey's Anatomy (2005) (TV) | - |
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