"The Muppets" return to prime time with a contemporary, documentary-style show that, for the first time ever, will explore the Muppets' personal lives and relationships, both at home and at work, as well as romances, break-ups, achievements, disappointments, wants and desires; a more adult Muppet show, for kids of all ages.

Follow Kermit the Frog and the rest of the Muppet gang as they produce late-night talk show, "Up Late with Miss Piggy". Although Kermit and Miss Piggy are officially broken up and dating other people, Kermit still serves as the Executive Producer of her talk show, which is proving to be a very challenging task. Miss Piggy is a star in her own right and spends more time canoodling with Hollywood's elite than actually working. Fozzie Bear is the warm-up comic / sidekick for the show but is also balancing a serious relationship with a human woman whose parents do not approve of their inter-species relationship. Meanwhile, The Great Gonzo, the head writer for 'Up Late,' is very single. With the help of the staff writers Pepe the King Prawn and Rizzo, Gonzo will explore the perils of online dating. Scooter, Dr. Teeth, Janice, Animal, Dr. Bunsen Honeydew and Beaker and the rest of the Muppets all have roles at "Up Late," but mostly just keep Kermit on his toes! After work, the crew usually heads over to Rowlf's Tavern to unwind, but of course the Muppet mayhem follows wherever they go.