Based on the New York Times bestselling novel, "Mrs. Fletcher" is a dual coming-of-age story, exploring the impact of internet porn and social media on the lives of an empty nest mother and her college freshman son.

As the series begins, Eve Fletcher (Kathryn Hahn), a mid-40s single mom who works as the executive director of a senior center, drops her only child off at college and returns home to a very empty house. Meanwhile, Eve's son Brendan (Jackson White), a popular (though sometimes clueless) jock, finds college is a little more complicated than he expected and struggles to make connections with his more socially and politically aware fellow students. As mother and son find themselves alone for the first time, this sharp, provocative series navigates themes of parenthood, sexuality, love, and identity in a cultural moment when attitudes about gender and sex are evolving rapidly.