Matthew Perry stars as Ben Donovan, the self-involved manager of a second-rate San Diego sports arena who begins to re-evaluate his life on his 40th birthday. Working alongside him is his boss and arena owner, Crystal-attractive, powerful and highly erratic; Alice-the cute, tomboyish marketing director and Ben's friend with benefits; Alonzo-a former basketball player, handsome and unbelievably happy; Ben's assistant, Heather-pretty, sweet, but terrifying because she once lit a boyfriend on fire; Crystal's son, Roman-sweet-faced, clueless and Ben's newest employee; and a hapless operations crew whom Ben refers to collectively as the "Steves."

Mr. Sunshine stars Matthew Perry (Friends) as Ben, Allison Janney (The West Wing) as Crystal, Andrea Anders as Alice, James Lesure as Alonzo, Nate Torrence as Roman and Portia Doubleday as Heather.