The show centers on Judge Harris, a hard-living, law-bending married man with a high-end call girl on the side, who suffers a mental breakdown and goes on a vigilante quest to find the rapist who tore his family apart. With no real evidence to go on, Pernell begins to rely on "visions" and "messages" he believes are being sent by God through Pernell's ventilator-bound son.

Hand of God also stars Dana Delany (Body of Proof) as the Judge's protective wife Crystal Harris, Garret Dillahunt (Justified) as KD, the born-again sociopath whose violent tendencies are exploited by Pernell, Andre Royo (The Wire) as the slick, smart, gregarious, and greedy mayor Robert 'Bobo' Boston, Alona Tal (Burn Notice) as Pernell's grieving daughter-in-law Jocelyn Harris, Julian Morris (Pretty Little Liars) as the questionable preacher Paul Curtis, Elizabeth McLaughlin (Betrayal) as the preacher's sultry girlfriend Alicia, and Emayatzy Corinealdi (Middle of Nowhere) as Pernell's call girl and confidante Tessie.

Hand of God returns with Golden Globe winner Ron Perlman (Sons of Anarchy), starring as Judge Pernell Harris. The hard-living, law-bending king of San Vicente, "Judge Maximum" has finally hit bottom as he faces trial for the murder of a cop. While his visions and the ghost of his dead son will slowly lead Pernell through a conspiracy that is bigger than he could have imagined, they will threaten his relationship with his wife and everything he holds dear. In this season 2, Judge Maximum must fight on two fronts - to restore his sanity and gain his freedom.