Corpses - cops - traps - cult - assassins - Pararibulitis - vampires - lottery ticket - kitten - corgi - everything is connected in this bizarre world. It all begins on the absolute worst day of Todd's life. After his drug dealing landlord trashes his car, he trudges onto a Seattle bus to make it to his job as a bellhop. Dispatched to the hotel penthouse, the horrific scene of murdered millionaire, Patrick Spring, begets a peculiar chain of events that makes him a person of great interest... and gets him sacked from his job.

Enter Dirk Gently, the fast talking, eccentric detective hired to investigate the case. Dirk, whose philosophy hinges on the interconnectedness of all things, wholly believes he and Todd are destined to untangle the mystery together, and tries his hardest to convince Todd to embrace the madness because let's face it, what else has he got going on... Once half-convinced, Todd's world is infiltrated by a collection of wild and dangerous characters who further complicate his life, all because of Dirk Gently.

In addition to Todd's ailing sister Amanda (Hannah Marks), a former punk-chick, now a Pararibulitis sufferer, there's Farah Black (Jade Eshete), a security officer assigned to protect the murder victim's daughter, and friend of Dirk Gently, The Rowdy 3 (Michael Eklund, Osric Chau, Viv Leacock and Zak Santiago), Yes, a quartet of psychic vampires who constantly target Dirk Gently, Zimmerfield (Richard Schiff) and Estevez (Neil Brown Jr.), detectives assigned to investigate the same complex case Dirk Gently was hired to investigate, Gordon Rimmer (Aaron Douglas), a loser cult leader with deep secrets, who's lost dog is tied to the case, and Colonel Riggins (Miguel Sandoval), the leader of a failed CIA secret experiment and his idiot officer, Sergeant Friedkin (Dustin Milligan) who are ordered to capture Dirk Gently.

Far away from the city, Ken (Mpho Koaho) too is having a really bad day. While minding his business of hacking into a mainframe to make a few bucks, a seemingly deranged assassin, Bartine "Bart" Curlish (Fiona Dourif) insinuates herself into his life... after she tries to murder him... because she mistook him for Dirk Gently... without actually knowing if he was Dirk Gently... because Bart is not a very thorough assassin. But she is a holistic one, that kills whomever the universe tells her to. And you guessed it, it's told her to kill Dirk Gently.

Based on Douglas Adams novel series "Dirk Gently's Holistic Detective Agency", written by Max Landis, this eight-episode series follows the bizarre adventures of eccentric "holistic" detective Dirk Gently (Samuel Barnett) and his reluctant assistant Todd (Elijah Wood), as they wend their way through one big, seemingly insane mystery, crossing unlikely paths with a bevy of wild and sometimes dangerous characters, each episode landing them a few random steps closer to uncovering the truth.