Ahead of Hugh's big day on Saturday, October 12, Ryan sent his longtime friend a sweet clip - and "The Greatest Showman" actor couldn't resist sharing the whole thing online, and also live at his birthday show in Indianapolis, Indiana.
"Hello Hugh, I was just going to wish you a happy birthday... and then I saw what you said, and in a word... hurtful, enjoy the show.. Hugh Jackman," Ryan said in the video, alluding to the "The Wolverine" star joking about Reynolds' singing at an earlier live show.
The "Deadpool" star, 42, then started singing "Happy Birthday," before concluding the video saying: "And I'm not f**king professionally trained Hugh Jackman you piece of s**t."
Captioning the video, Hugh wrote online: "At first I thought - Ugh, now I have to actually apologise. But then."
In addition to the personal message, Ryan also shared a public post with a cheeky birthday message, sharing a snap of the pair and putting a cake sticker over his Aussie pal's face.
Hugh later hit back, but all in good fun, reposting the picture with an animated version of American TV star Judge Judy rolling her eyes on top of Ryan's face.