The survivors of the Ghostface killings think they've left their small-town terror behind, only to find that the mask follows them to the heart of New York City in this chilling new chapter. Melissa Barrera and Jenna Ortega return as the Carpenter sisters, attempting to forge a new life alongside fellow survivors Jasmin Savoy Brown and Mason Gooding, but a more brutal and cunning Ghostface emerges from the urban shadows. With the rules of the franchise rewritten, the group must navigate a sprawling metropolis where danger lurks around every corner and trust is a fragile commodity. Veteran reporter Gale Weathers, played by Courteney Cox, finds herself drawn back into the bloody mystery, while new faces like Samara Weaving and Dermot Mulroney enter the fray, each with their own secrets. Directed by Matt Bettinelli-Olpin and Tyler Gillett, the film escalates the tension and set pieces to terrifying new heights, blending razor-sharp suspense with a deep reverence for the iconic Scream legacy. As the body count rises across the city that never sleeps, the core quartet must uncover the killer's connection to the past if they hope to survive a nightmare that has learned from every stab that came before.