It's a Boy Girl Thing is a high-jinx romantic comedy about next-door neighbours who live worlds apart. Woody Deane and Nell Bedworth, life-long sworn enemies, wake up one day to find themselves in a very strange place: each others bodies.

In their switched identities, each sets about to destroy the other's high school reputation. When they start to succeed they get more than they bargained for. Sometimes falling in love can be an out of body experience.