Zachary Quinto stars as a dentist who teams up with a feisty would-be assassin (Carla Gugino) to put the final touches on the plan to kill his wife. Once he makes a play for the assassin's payment, he unknowingly sets off a chain of events that fuels a cross-town journey through the many lounges, bars, strip clubs and the occasional nudist ping pong club scattered across Los Angeles. Along the way, we are introduced to a series of idiosyncratic characters, from pickpocket and gangsters (Aaron Tveit, Danny DeVito) to exotic dancers (Emmanuelle Chriqui, Alexis Bledel), from ex-cons (Robert Forster) to cops (Josh Hartnett, Gil Bellows), with the odd hatcheck girl (Rosario Dawson) and bartender (Amber Valletta) thrown in for good measure.