A beautiful young woman, driven mad by her past. An ambitious doctor on a mission to succeed. An esteemed mentor with a revolutionary cure. Let the mind games begin...

Seduced by the challenge of an impossible case, the driven Dr. Jung (Michael Fassbender) takes the unbalanced yet beautiful Sabina Spielrein (Keira Knightley) as his patient. Jung's weapon is the method of his master, the renowned Sigmund Freud (Viggo Mortensen). Both men fall under Sabina's spell. Into the mix comes Otto Gross (Vincent Cassel), a debauched patient who is determined to push the boundaries.

Jung gives in to lust and a passionate affair begins. Sabina becomes the catalyst for Jung's inspired theories. Meanwhile Freud goes further, delving into Sabina's brilliant mind until she can take the situation no longer. The bonds between the trio shatter. Driven by desire and revenge, with their reputations at stake, Freud and Jung embark on a battle of wills.

In this dangerous game of sex and intellect, the price will be Sabina's soul.