The story is set along the Mexico/California Border, principally in Imperial Beach, CA. It concerns a female DEA agent, Dara Maren, who, in protecting her petty criminal younger brother, gets herself arrested and imprisoned in a nightmarish penal colony outside Tijuana.

While she's in prison, Dara's brother is murdered by a drug lord who's creating a new DNA-altering drug made from human spinal fluid.... tapped from the living.Hundreds of dead bodies are turning up along the Border, and the drug addicts become something less than human. The drug is so addictive that even law enforcement and government officials are on the stuff. A rogue FBI agent bribes the prison officials to let Dara out to avenge her brother's murder as well as bring down the drug lord in ways the Feds cannot. When Dara comes out of prison, she is not the same person who went in. The catch? She only gets a 60-hour get-out-of-jail card and must return to the prison to serve out her 20-year sentence, or the FBI agent, who got her out, must take her place.