Forty years ago, artist Alex Carver (Morgan Freeman) bought a run-down apartment in a sketchy part of Brooklyn with his wife, schoolteacher Ruth (Diane Keaton). Today, their neighborhood is now very hip and their apartment worth a small fortune. The now - retired Ruth and Alex haven't changed - they are still as much in love as ever. But they have let Ruth's niece Lily (Cynthia Nixon), a real estate agent, list their property to see what the market might bear.

On the eve of their open house, the Brooklyn Bridge is rumored to be under a terrorist attack, sending the media into a frenzy and people's attitudes about living in New York. Closer to home, Dorothy, the Carver's beloved dog, is suddenly having trouble walking.

While Dorothy is having expensive treatment at the vet, Ruth convinces Alex to go apartment hunting in Manhattan, where they miraculously come across an ideal place they might actually be able to afford. As the world around them seems to mirror their own chaos and confusion, Ruth and Alex realize the same bond of love that has kept them together all these years will allow them to see their way through this crazy weekend as well.