"Prime" is a sophisticated, character comedy set in New York City about Rafi (Thurman), a recently divorced 37-year-old career woman from Manhattan, and what happens when Dave (Greenberg), a talented 23-year-old painter from Brooklyn, falls in love with her.

Part counselor, part Jewish mother, Rafi's therapist Lisa (Meryl Streep) is gingerly helping Rafi out of her post-divorce slump and through the urgent alarm of her ticking biological clock. Although doubtful that Rafi's new fling (he is 23, after all) is an appropriate partner in the long term, Lisa encourages her patient to enjoy it and have fun (he is 23, after all!). But once Lisa accidentally discovers that Rafi's new boyfriend is, in fact, her son, Dave, she finds it increasingly difficult to act the good therapist while hearing intimate details of her son's love life. Soon, the secret is out and cultures clash, complications arise, civil arguments erupt and a storm of opinions swirl around the couple at the center of all this comic fuss.

"Prime" looks at love from everyone's point of view--friends, relatives and in this case, Rafi's therapist (Streep)--and follows all who come apart, and some who pull it together, when two people fall in love.