At the annual Springfield Chili Cook-Off, Homer eats super-spicy chili made with a dangerous Guatemalan pepper grown by mental patients. The pepper has a powerful hallucinogenic effect and Homer wanders off into the darkest, strangest regions of his mind. Guided by a talking coyote, he goes on a voyage of self-discovery and realizes that he must find his soul mate. When he emerges from his fantastic trip, he returns home to Marge, who is furious at him for disappearing. Marge yells at Homer and tells him that she is not his soul mate, which sends Homer on another voyage to find out who is. Is Barney Homer's soul mate? Is Moe? Is some guy who placed a personal ad? Homer wanders the streets of Springfield, eventually winding up at the lighthouse at the edge of town, under the impression that the lighthouse keeper is his soul mate. Ascending the stairs to the top of the lighthouse, Homer discovers that the lighthouse is operated by a computer. Enraged, Homer shatters the lighthouse's giant light. As a giant barge approaches, Marge arrives on the scene and helps Homer save the boat. She then tells Homer that of course she's his soul mate.
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