The provocative medical drama follows the doctors and nurses at Chastain Memorial Hospital, as they face personal and professional challenges and fight for their patients' health. The new season picks up as DR. Conrad Hawkins (Matt Czuchry) and Nurse Practioner Nicolette Nevin (Emily VanCamp) tie the knot in an intimate and beautiful wedding, strengthening their already powerful bond. Meanwhile, Chastain is transitioning from private to public hospital, causing the hero doctors to fight to fix the broken machine from the inside. DR. Randolph Bell (Bruce Greenwood) finds himself mining his own past to find his estranged former stepson, elite plastic surgeon DR. Jake Wong (guest star Conrad Ricamora).
Bell attempts to bring Dr. Wong to Chastain to increase the number of world-class surgeries at the hospital and to repair their complicated past. Additionally, as star surgical resident DR. Mina Okafor (Shaunette Renée Wilson) and her brilliant mentor, DR. AJ Austin (Emmy Award nominee Malcolm-Jamal Warner), grow closer than ever, they must learn to maintain a professional relationship within the walls of the hospital.
In fourth season premiere, After a long wait, Conrad and Nic prepare for their wedding day with the support of their family and friends. Meanwhile, flashbacks to the early days of the COVID-19 crisis shine a light on the heroism of the doctors and the toll the virus took on everyone at Chastain Memorial.
