The pregnant Anna flees from an infected man and locks inside a room. When the man breaks in, she stabs him to death. At the same time, she delivers her baby girl. Out of the blue, Marlene and the Fireflies arrive and Anna delivers the baby Ellie to her and asks Marlene to shoot her before the transformation. Joel and Ellie are emotionally attached to each other and continue their journey to find the hospital where the Fireflies will research Ellie to find the cure. They are surprised by a group of men that hit Joel on the head. When he awakes, he sees Marlene and learns that he was captured by the Fireflies. He asks her how Ellie is, and Marlene tells him that she will be sacrificed by the doctor to create the cure to the mankind. Will Joel accept the fate of Ellie?
