Shaun's (Freddie Highmore) proposed treatment for a homeless patient puts him and Dr. Kalu (Chuku Modu) in Dr. Andrews' (Hill Harper) crosshairs. Claire (Antonia Thomas) tries to overcome Dr. Melendez's (Nicholas Gonzalez) reluctance to do a risky heart operation. Dr. Glassman (Richard Schiff) faces a difficult decision about his health.