It's a miracle when a trauma patient survives the trip to the hospital, putting the pressure on Dr. Rhodes (Colin Donnell) to keep the man alive. Dr. Choi (Brian Tee) and Dr. Manning (Torrey DeVitto) have difficulty diagnosing the location of infection in a paralyzed patient. Dr. Reese (Rachel DiPillo) must find purpose for a grieving widower who relies on a superhero costume.
Meanwhile, April (Yaya DaCosta) pushes Dr. Halstead (Nick Gehlfuss) to use unproved medications to help a patient with no other options.
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