"Wu Assassins" follows Kai Jin (Iko Uwais), a young Chinatown chef in present day San Francisco, as he becomes entangled with the Chinese Triad's pursuit of deadly ancient powers known as the "Wu Xing." After an encounter with a mystical spirit, Kai reluctantly becomes the Wu Assassin, using his enhanced martial arts skills to recover supernatural powers from five modern day criminals threatening to use them to destroy the world.