In the climactic episode, Alex Reid (Erica Durance) is pulled into the ER on one of its busiest nights of the year - and she is about to find out if a full moon really does cause strange things to happen. First up is a chance encounter with Joel Goran (Daniel Gillies) that has Alex questioning if the spark between them is reigniting.
When her patient starts exhibiting contradicting symptoms, Alex pulls Joel and Maggie Lin (Julia Taylor Ross) in on the case to help her solve the mystery - and the results are shocking. Meanwhile, Charlie Harris (Michael Shanks) tries to figure out where he wants to stand with his ex-wife Dawn Bell (Michelle Nolden), and is side-tracked when an in-patient tries to convince him she's dead.
Dr. Jimmy Dey (Mac Fyfe) and Rian (Danso Gordon) assist in the woman's treatment, and afterward Charlie has a renewed sense of what it means to be alive. Meanwhile, Zach Miller (Benjamin Ayres) gets a surprise visit from his son that leads him to reāevaluate his actions as a father.