Cliff and Rita seek out Jane, who is under the control of Karen, a perky but unstable personality with the power to make people love her. In their search for Caulder, Larry and Vic come across a sentient, genderqueer, teleporting street named Danny, which is being hunted by the Bureau of Normalcy. Larry remembers his own experience with the Bureau, which experimented on him in the 1960s after his accident and gave him the first glimpse of his negative energy spirit.
Former Bureau agent Morris Wilson has become a drag queen named Maura Lee Karupt who helps keep Danny going by sustaining a party atmosphere. She faces off with her former partner, Agent Darren Johnson, to stop the Bureau's persecution of Danny. Jane and Karen fight for control of her mind, but soon Jane snaps, leaving her catatonic while her consciousness is dragged into the Underground.