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Christina Applegate Quits 'Up All Night' Following Format Change

February 9, 2013 (2:20 am) GMT
As the comedy is swicthing from a single-camera to a multi-camera format, the Regan depicter decides 'to move on to other endeavors.'

"" is losing one of its leads. has just shocked fans with her decision to leave the NBC comedy series as the show prepares to switch visual formats in the second part of its second season.

"It's been a great experience working on 'Up All Night', but the show has taken a different creative direction and I decided it was best for me to move on to other endeavors," Applegate says in a statement.

"Working with (executive producer) Lorne Michaels has been a dream come true and I am grateful he brought me into his TV family. I will miss the cast, producers and crew, and wish them the best always."

Starting as a single-camera comedy without a studio audience, "Up All Night" is going to switch to become a multi-camera format which features a studio audience in the second part of season 2. The show hasn't filmed any new episodes with live audience.

Applegate plays Reagan Brinkley, one-half of the major couple, on the sitcom, starring alongside who portrays Reagan's husband. Some say the show is dead following the 41-year-old actress' departure, but other sources say the show could go on with "Friends" alumna as a potential replacement.

NBC has neither commented on Applegate's exit nor explained the future of the comedy series.

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