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Michelle Monaghan will play the lead female opposite Patrick Dempsey in Columbia Pictures' rom-com flick "Made of Honor."

AceShowbiz - Finally the leading actress for "Made of Honor" is found. The Hollywood Reporter has learned that Michelle Monaghan has eagerly signed on to fill in the part, which thereby will pair her with "Grey's Anatomy" star Patrick Dempsey.

A production of Columbia Pictures, the rom-com flick finds Monaghan playing a woman named Claire, the longtime friend of Dempsey's character Tom whom she asks to be her 'maid' of honor for her wedding. The guy, who finally learns that she is actually the girl of his dream, reluctantly agrees -- only so he can try to stop the wedding and win her over before it's too late.

Production is slated to begin in April this year with Paul Weiland directing from script written by Deborah Kaplan and Harry Elfont based on an original screenplay by Adam Sztykiel. Seating as producer is Neal Moritz of Original Film with Aaron Kaplan, Sean Perrone, and Tania Landau all executive producing.

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