(*): W=Win, N=Nomination
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2019 | N | Video of the Year | "Babe" | Taylor Swift |
| 2013 | N | Vocal Duo of the Year | - | - |
| 2012 | N | Vocal Duo | - | - |
| 2011 | W | Top Vocal Duo of the Year | - | - |
| 2011 | N | Video of the Year | "Stuck Like Glue" | - |
| 2010 | N | Top Vocal Duo of the Year | - | - |
| 2009 | W | Top Vocal Duo | - | - |
| 2009 | N | Vocal Event of the Year | "Life in a Northern Town" | Little Big Town, Jake Owen |
| 2008 | W | Single Record of the Year | "Stay" | - |
| 2008 | N | Video of the Year | "Stay" | - |
| 2008 | N | Song of the Year | "Stay" | Jennifer Nettles (songwriter) |
| 2008 | N | Top Vocal Duo | - | - |
| 2007 | N | Top Vocal Duo | - | - |
| 2006 | W | Top New Duo or Vocal Group | - | - |
| 2006 | N | Song of the Year | "Baby Girl" | Kristian Bush, Kristen Hall, Jennifer Nettles (songwriters) |
| 2006 | N | Single Record of the Year | "Baby Girl" | - |
| 2006 | N | Album of the Year | "Twice the Speed of Life" | - |
| 2006 | N | Top Vocal Group | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2011 | N | Artist of the Year: Duo or Group | - | - |
| 2011 | N | Single of the Year: Duo or Group | "Stuck Like Glue" | - |
| 2010 | N | Touring Headline Package of the Year | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2010 | N | Artist of the Year: Duo or Group | - | - |
| 2009 | N | Favorite Country Band/Duo/Group | - | - |
| 2008 | N | Favorite Country Band/Duo/Group | - | - |
| 2005 | W | Favorite Breakthrough New Artist | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2011 | N | Top Country Album | "The Incredible Machine" | - |
| 2011 | N | Top Country Song | "Stuck Like Glue" | - |
| 2006 | N | Duo/Group Country Artist of the Year | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2019 | N | Collaborative Video of the Year | "Babe" | Taylor Swift |
| 2019 | N | Duo Video of the Year | "Babe" | Taylor Swift |
| 2012 | N | Duo Video of the Year | "Tonight" | - |
| 2011 | W | Duo Video of the Year | "Stuck Like Glue" | - |
| 2011 | N | Video of the Year | "Stuck Like Glue" | - |
| 2010 | N | Duo Video of the Year | "Keep You" | - |
| 2010 | N | Duo Video of the Year | "Nightswimming/Joey" | - |
| 2009 | W | Duo of the Year | "All I Want to Do" | - |
| 2009 | N | CMT Performance of the Year | "Life in a Northern Town" | Little Big Town, Jake Owen |
| 2009 | N | Collaborative Video of the Year | "Life in a Northern Town" | Little Big Town, Jake Owen |
| 2009 | N | Duo of the Year | "Already Gone" | - |
| 2009 | N | Video of the Year | "All I Want to Do" | - |
| 2008 | W | Duo Video of the Year | "Stay" | - |
| 2008 | N | Video of the Year | "Stay" | - |
| 2008 | N | Tearjerker Video of the Year | "Stay" | - |
| 2008 | N | Performance of the Year | "Stay" [at 2007 CMT Music Awards (CMT)] | - |
| 2007 | W | Duo Video of the Year | "Want to" | - |
| 2007 | N | Video of the Year | "Want to" | - |
| 2006 | N | Breakthrough Video of the Year | "Something More" | - |
| 2006 | N | Group/Duo Video of the Year | "Just Might (Make Me Believe)" | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2018 | N | Music Video of the Year | "Babe" | Taylor Swift |
| 2018 | N | Vocal Duo of the Year | - | - |
| 2013 | N | Vocal Duo of the Year | - | - |
| 2012 | W | Vocal Duo of the Year | - | - |
| 2011 | W | Vocal Duo of the Year | - | - |
| 2010 | W | Vocal Duo | - | - |
| 2009 | W | Vocal Duo of the Year | - | - |
| 2009 | N | Album of the Year | "Love on the Inside" | - |
| 2008 | W | Vocal Duo of the Year | - | - |
| 2008 | N | Music Video of the Year | "Stay" | - |
| 2008 | N | Musical Event of the Year | "Life in a Northern Town" | Little Big Town, Jake Owen |
| 2008 | N | Single of the Year | "Stay" | - |
| 2008 | N | Entertainer of the Year | - | - |
| 2007 | W | Vocal Duo of the Year | - | - |
| 2006 | N | Vocal Group of the Year | - | - |
| 2006 | N | - | - | - |
| 2005 | N | Single of the Year | "Baby Girl" | - |
| 2005 | N | Vocal Group of the Year | - | - |
| 2005 | N | - | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2010 | N | Best Country Performance by a Duo or Group with Vocals | "It Happens" | - |
| 2009 | W | Best Country Performance by a Duo or Group with Vocals | "Stay" | - |
| 2009 | N | Best Country Collaboration with Vocals | "Life in a Northern Town" | Jake Owen, Little Big Town |
| 2006 | N | Best New Artist | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2018 | N | Group of 2018 | - | - |
| 2018 | N | Country Artist of 2018 | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2005 | N | Song of the Year/Country Radio | "Baby Girl" | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2010 | N | Choice Music: Country Group | - | - |
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